diff --git a/SPECS/kpatch.spec b/SPECS/kpatch.spec
index 3f91cac..49e0e95 100644
--- a/SPECS/kpatch.spec
+++ b/SPECS/kpatch.spec
@@ -21,6 +21,11 @@ Patch100:       https://github.com/dynup/kpatch/pull/1231.patch
 # kpatch-dnf backports
 Patch200:	0200-Makefile-set-install-permission-modes.patch
 
+# kpatch is only supported on x86_64 and ppc64le
+# https://github.com/dynup/kpatch/#supported-architectures
+ExcludeArch:    aarch64
+ExcludeArch:    s390x
+
 %description
 kpatch is a live kernel patch module manager.  It allows the user to manage
 a collection of binary kernel patch modules which can be used to dynamically
@@ -104,6 +109,7 @@ echo -e "\t$ dnf kpatch auto"
 %changelog
 * Wed Oct 13 2021 Davide Cavalca <dcavalca@centosproject.org> - 0.9.4-1.7
 - Backport PR#1231 for clang PGO support
+- Exclude aarch64 and s390x as kpatch is not supported there
 
 * Fri Aug 27 2021 Davide Cavalca <dcavalca@centosproject.org> - 0.9.4-1.6
 - Add Obsoletes to properly replace kpatch with kpatch-runtime on upgrades