mysql 5.5 does not export a HAVE_OPENSSL symbol, thus breaking MySQL-python's rather-misguided-anyway conditional compilation for SSL support. Since we have no intention of ever shipping a non-SSL-enabled mysql in Fedora/RHEL, we can just drop the conditionals, pending some other fix upstream. (Since mysql_ssl_set is supposed to exist anyway, this might well be a suitable fix for upstream too.) diff -Naur MySQL-python-1.2.5.orig/_mysql.c MySQL-python-1.2.5/_mysql.c --- MySQL-python-1.2.5.orig/_mysql.c 2014-01-02 13:52:50.000000000 +0100 +++ MySQL-python-1.2.5/_mysql.c 2015-10-15 17:14:08.495603713 +0200 @@ -551,10 +551,8 @@ MYSQL *conn = NULL; PyObject *conv = NULL; PyObject *ssl = NULL; -#if HAVE_OPENSSL char *key = NULL, *cert = NULL, *ca = NULL, *capath = NULL, *cipher = NULL; -#endif char *host = NULL, *user = NULL, *passwd = NULL, *db = NULL, *unix_socket = NULL; unsigned int port = 0; @@ -618,18 +616,12 @@ #endif if (ssl) { -#if HAVE_OPENSSL PyObject *value = NULL; _stringsuck(ca, value, ssl); _stringsuck(capath, value, ssl); _stringsuck(cert, value, ssl); _stringsuck(key, value, ssl); _stringsuck(cipher, value, ssl); -#else - PyErr_SetString(_mysql_NotSupportedError, - "client library does not have SSL support"); - return -1; -#endif } Py_BEGIN_ALLOW_THREADS ; @@ -667,11 +659,9 @@ if (local_infile != -1) mysql_options(&(self->connection), MYSQL_OPT_LOCAL_INFILE, (char *) &local_infile); -#if HAVE_OPENSSL if (ssl) mysql_ssl_set(&(self->connection), key, cert, ca, capath, cipher); -#endif conn = mysql_real_connect(&(self->connection), host, user, passwd, db, port, unix_socket, client_flag);